Pharmaceutical Chemistry Research Group

Dr. Jamshed Iqbal

Designation: Professor
Email: drjamshed@cuiatd.edu.pk
Phone No. : 0992-383591-6
Role: Faculty
Research Interests:

Drug development Based on Enzyme Inhibition 

Academics/ Degrees

  • Postdoc           2009-2010       Chinese Academy of Sciences, China
  • Postdoc           2005-2009       University of Bonn, Germany
  • PhD                 2005                University of Bonn, Germany
  • MSc                 2000                University of Strathclyde, Glasgow, UK
  • MSc                 1996                Bahauddin Zakariya University, Multan
  • MPhil              1999                 Quaid-i-Azam University, Islamabad

Profile/Bio

  • Professor                     2013 till date               CUI Abbottabad
  • Associate Professor     2007 - 2013                COMSATS IIT, Abbottabad
  • Lecturer                       1999- 2000                  Islamia University Bahawalpur

Publications/Papers

2023


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2022


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2021


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Patent

2020


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2019


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Book/Chapter



2018


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2017


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2016


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2015


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2014


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2013


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2012


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2010


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2003




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1998




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Associations/Memberships

  • Fellow of Royal Society of Chemistry (FRSC)
  • Fellow of the Pakistan Academy of Science (FPAS) 
  • Fellow of the Chemical Society of Pakistan (FCSP)
  • Member of Royal Pharmaceutical Society of Great Britain (RPSGB) 
  • Member of German Pharmaceutical Society (DPhG) 
  • Member of Pakistan Society for Biochemistry and Molecular Biology (PSBMB)

Awards/ Appreciations

AWARDS/APPRECIATIONS

  • HEC Outstanding Research Award for 2021 in the field of Life Sciences, Biological Sciences, Health Sciences, Pharmacy, Agriculture, or Veterinary Sciences
  • Prestigious Fellow of Royal Society of Chemistry (FRSC) conferred by the Royal Society of Chemistry, United Kingdom.
  • Pakistan Academy of Sciences Gold Medal for 2017.
  • Tamgha-i-Imtiaz, 2012, Pakistan's highest civilian decorations awarded by president of Pakistan.
  • Best Researcher Award at Campus Level, COMSATS University Islamabad, Abbottabad Campus, Pakistan, 2015.
  • Best Researcher Award at Campus Level, COMSATS University Islamabad, Abbottabad Campus, Pakistan, 2020.
  • Research Productivity Award for 2011, 2012, 2013, 2014, 2015, 2016, 2017 & 2018 by COMSATS Institute of Information Technology.
  • Research Productivity Award for 2013, 2014, 2015, 2016 & 2017 by Pakistan Council for Science and Technology (PCST), Islamabad. In 2015 and 2016, the award was in the highest category “A”. However, in 2017, Prof. Iqbal won the same award in category “A” having 10.82 score by getting 21st position out of 2896 candidates in various disciplines throughout the Country. Moreover, Prof. Iqbal got 2nd position in Productive Scientists of Pakistan (PSP) out of 2631 Pakistani Scientist in various disciplines among the country.
  • Most Cited Paper 2006-2009 Award from Elsevier Publishers, Christa E. Müller, Jamshed Iqbal, Younis Baqi, Herbert Zimmermann, Anita Röllich, Holger Stephan. “Polyoxometalates - a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorganic & Medicinal Chemistry Letters (2006) 16 (23), 5943-5947
  • Pakistan 50th Anniversary Fund Scholarship for M.Sc. at University of Strathclyde, Glasgow, UK.
  • DAAD, STIBET Scholarship for Postdoc at University of Bonn, Germany.
  • CAS Research Fellowship for International Young Researchers. Research Fellow (2009-2010): Dalian Institute of Chemical Physics, CAS, 457 Zhongshan Road, 116023, Dalian, Chinese Academy of Sciences.
  •  International Young Researchers award given by President of Chinese Academy of Sciences, China.
  • Merit Scholarship (University Grants Commission of Pakistan) for M.Phil. studies at Quaid-i-Azam University, Islamabad.
  • Travel grant from GlaxoSmithKline for participation in 8th International Symposium on Adenosine and Adenine Nucleotides. University of Ferrara, Italy, May 24 - 28, 2006.
  • Travel grant from GlaxoSmithKline for Second Joint Italian-German Purine Club Meeting Leipzig, Germany, September 12-15, 2007.
  • Travel grant from GlaxoSmithKline for Microscale bio-separations and methods for systems biology, Berlin, Germany, March 9-13, 2008 (MSB 2008).
  • Travel grant from GlaxoSmithKline for Purines 2008 Meeting 29th June – 2nd July 2008, Copenhagen, Denmark. 

SEMINARS/ WORKSHOPS DELIVERED

  • Prof. Dr. Jamshed Iqbal, Invited Lecture 18th Symposium on Purine and Pyrimidine Metabolism in Man orginzed by “The Purine and Pyrimidine Society” from 12th to 14th of June 2019 in Lyon, France
  •  Prof. Dr. Jamshed Iqbal, Keynote Speaker in International Conference on Chemical Sciences, organized by Department of Chemistry Quaid i Azam University, Islamabad, during April 24-26, 2019.
  • Prof. Dr. Jamshed Iqbal, Keynote Speaker in 3rd International Conference on Recent Innovations in Pharmaceutical Sciences (ICRIPS-2019), March 13-14, 2019, Riphah International University, Islamabad, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Keynote Speaker in 1st International Conference on “Advancements in Biotechnology & Biocomputing” organized by Department of Biological Sciences, International Islamic University, Islamabad during 7-9 February, 2019.
  • Prof. Dr. Jamshed Iqbal, Keynote Speaker in 1st Annual Conference on “The Current Usage of Nanotherapeutics & Biodrugs” organized by Department of Biological Sciences, International Islamic University, Islamabad during 12-13 December, 2018.
  • Prof. Dr. Jamshed Iqbal, Invited lecture in International Conference entitled “Purines 2018 International - Basic and translational science on purinergic signaling and its components for a healthy and better world” during 19-22 June, 2018 in Brazil.
  • Prof. Dr. Jamshed Iqbal, Plenary talk in two-day National conference on “Recent Advancements in Pharmaceutical Sciences: Innovative Drug Research for Better Cure” during 7-8 March, 2018, organized by College of Pharmacy, University of Sargodha, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Invited speaker at “3rd International Health Trigon Summit, Inter-Professional Cooperation in Pharmacotherapy” 2018 held during 17-18th April, 2018 organized by The University of Lahore, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Plenary speaker in International Conference on Chemical and Pharmaceutical Sciences: Recent Approaches in Research & Applications, to held on 17-19 January, 2018 at Forman Christian College (A Chartered University) Lahore, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Plenary speaker in 1st International Conference on Advances in Drug Discovery and Development'' to held on 3-5 January, 2018 at NARC, Islamabad, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Plenary speaker in 2nd International Conference on Recent Innovations in Pharmaceutical Sciences (ICRIPS-2017), November 15-16, 2017, Riphah International University, Islamabad, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Plenary speaker in three-day international conference on “Current Research in Chemical & Pharmaceutical Sciences” January 18-20, 2017, Forman Christian College (A Chartered University) Lahore, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Plenary speaker in 1st Biennial Conference on “New Horizons in Drug Discovery and Pharmaceutical Scieces” December 15, 2016, Abbottabad University of Science and Technology, Abbottabad.
  • Prof. Dr. Jamshed Iqbal, Invited Speaker in International Symposium on “Modern Strategies in Drug Discovery & Vaccine Design” December 2-3, 2016 at Lahore University of Management Sciences, Lahore.
  • Prof. Dr. Jamshed Iqbal, 1st International Conference on “Recent Innovations in Pharmaceutical Sciences”, March 3- 5, 2015, Riphah International University, Islamabad, Pakistan.
  • Prof. Dr. Jamshed Iqbal, International Conference on “Exploring New Avenues In Medicinal Chemistry: Opportunities And Challenges” January 21-23, 2015, Forman Christian College (A Chartered University) Lahore, Pakistan.
  • Prof. Dr. Jamshed Iqbal, Seminar on “Enzyme Inhibitors as Drug Targeting Challenges and Opportunities” November 28, 2014, Riphah International University, Islamabad, Pakistan.
  • Dr. Jamshed Iqbal, 14th Asian Symposium On Medicinal Plants, Spices and other Natural Products (ASOMPS), December 9-12, 2013, H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
  • Dr. Jamshed Iqbal, 11th Shokat Khanam Cancer Symposium, November 9-11, 2012, Lahore, Pakistan.
  • Dr. Jamshed Iqbal, International Scientific Spring (ISS) -2012 at National Centre for Physics, Islamabad from March 5-9, 2012 and Workshop on Nano Technology on March 10, 2012.
  • Jamshed Iqbal, Rabia Raza, Abdul Matin, Sundas Sarwar, Maria Barsukova-Stuckart, Masooma Ibrahim, Ulrich Kortz. Polyoxometalates as potent and selective inhibitors of alkaline phosphatases with profound anticancer and amoebicidal activities. 11th Shokat Khanam Cancer Symposium, November 9-11, 2012, Lahore, Pakistan.
  • Rabia Raza, Jamshed Iqbal, Abdul Matin, Sundas Sarwar, Maria Barsukova-Stuckart, Masooma Ibrahim, Ulrich Kortz, Polyoxotungstates as inhibitors of cancer regulating enzymes. 11th Shokat Khanam Cancer Symposium, November 9-11, 2012, Lahore, Pakistan.
  • Dr. Jamshed Iqbal, 9th International and 21st national Chemistry Conference, March 14-16, 2011, University of Karachi, Karachi, Pakistan.
  • Dr. Jamshed Iqbal, 9th International and 21th National Chemistry Conference, March 14-16, 2011, Jointly organized by H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences and Department of Chemistry, University of Karachi, Karachi, Pakistan.
  • Rabia Raza and Jamshed Iqbal, Development of enzyme immobilized micro-assay in capillary electrophoresis for characterization and inhibition studies of alkaline phosphatase. 9th International and 21st national Chemistry Conference, March 14-16th, 2011. University of Karachi, Karachi, Pakistan.
  • Miriam Schlenk, Minka Paskaleva, Jamshed Iqbal, Jürgen Gäb, Michael Gütschow, Christa E. Müller. Benzothiazinones – a new class of potent A1-adenosine receptor antagonists. DPhG-Jahrestagung in Braunschweig, 2010 Germany.
  • Jamshed Iqbal and Christa E. Müller. High-sensitivity capillary electrophoresis for monitoring of ecto- purine nucleoside phosphorylase and ecto-adenosine deaminase reactions by large-volume sample stacking. Asia-Pacific International Symposium on Lab on chip. Shanghai, 2009, China.
  • Sabrina Gollos, Fabian Heisig, Sven Jan Freudenthal, Andrea Behrenswerth, Jamshed Iqbal, Ralf Brune, Markus Sauer, Christa E. Müller. New Fluorescent-Labeled adenosine receptor ligands. Purinergic Receptors: New Frontiers for Novel Therapies, Third Joint Italian-German Purine Club Meeting, July 17-20, 2009 Camerino, Italy.
  • Younis Baqi, Stefanie Weyler, Hillmann, Petra, Umbach, Frank, Jamshed Iqbal, Kaulich, Marko, Christa E Müller. Anthraquinones: combinatorial synthesis and structure-activity relationships as non-nucleotide-derived P2Y2 receptor antagonists. Purines 2008 Meeting June 29 – July 2, 2008, Copenhagen, Denmark.
  • Jamshed Iqbal, Younis Baqi, Stefanie Weyler, Herbert Zimmermann, Christa E. Müller. Anthraquinones: structure-activity relationships as inhibitors of ecto-nucleoside triphosphate diphospho-hydrolases (E-NTPDases). Purines 2008 Meeting June 29 – July 2, 2008, Copenhagen, Denmark.
  • Jamshed Iqbal, Aileen F. Knowles, Christa E. Müller. Ecto-nucleoside triphosphate diphosphohydrolase (NTPDase2) immobilized on a polyacrylamide-coated capillary: on-line monitoring of the enzymatic reaction and screening of inhibitors by capillary. Microscale bioseparations and methods for systems biolog, Berlin, Germany, March 9-13, 2008.
  • Christa E. Müller, Andreas Brunschweiger, Younis Baqi, Sang-Yong Lee, Jamshed Iqbal, Herbert Zimmermann. Development of Ecto-5’-nucleotidase inhibitors as potential new anti-cancer drugs. XXth International Symposium on Medicinal Chemistry EFMC-ISMC 2008 Vienna, Austria, August 31-September 4, 2008.
  • Andreas Brunschweiger, Jamshed Iqbal, Mercedes N. Munkonda, Sang-Yong Lee, Herbert Zimmermann, Christa E. Müller. Synthesis and characterization of nucleotide mimetics as inhibitors of ecto-5’-nucleotidase and NTPDase1. Deutschen Pharmazeutischen Gesellschaft, Bonn, Germany, October 8-11, 2008.
  • Jamshed Iqbal, Younis Baqi, Stefanie Weyler, Herbert Zimmermann, Christa E. Müller. Anthraquinones: structure-activity relationships as inhibitors of ecto-nucleoside triphosphate diphospho­hydrolases (E-NTPDases). Deutschen Pharmazeutischen Gesellschaft, Bonn, Germany, October 8-11, 2008.
  • Younis Baqi, Stefanie Weyler, Hillmann Petra, Frank Umbach, Jamshed Iqbal, Kaulich Marko, Christa E. Müller. Anthraquinones: combinatorial synthesis and structure-activity relationships as non-nucleotide-derived P2Y2 receptor antagonists. Deutschen Pharmazeutischen Gesellschaft, Bonn, Germany, October 8-11, 2008.
  • Anne Lehr, Younis Baqi, Herbert Zimmermann, Jamshed Iqbal, Christa E. Müller. Testing of novel Ar (Alk)ylaminoanthraquinone derivatives as inhibitors of Ecto-5’-nucleotidase. Deutschen Pharmazeutischen Gesellschaft, Bonn, Germany, October 8-11, 2008.
  • Sabrina Gollos, Fabian Heisig, Sven J. Freudenthal, Jamshed Iqbal, Ralf Brune, Markus Sauer, Christa E Müller. A Simple route to new, functionalized Bodipy Derivatives. Deutschen Pharmazeutischen Gesellschaft, Bonn, Germany, October 8-11, 2008.
  • Andreas Brunschweiger, Jamshed Iqbal, Mercedes N. Munkonda, Jean Sévigny, Aileen F. Knowles.; Christa E. Müller. Synthesis and structure-activity relationships of 5'-substituted uridine and adenosine derivatives as Ecto-5'-nucleotidase inhibitors. Second Joint Italian-German Purine Club Meeting, Leipzig, Germany, September 12-15, 2007.
  • Miriam Fast, Jamshed Iqbal, Herbert Zimmermann, Jean Sévigny, Christa E. Müller. Capillary electrophoresis-based nano-scale assays for monitoring ecto-5’-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes. Second Joint Italian-German Purine Club Meeting Leipzig, Germany, September 12-15, 2007.
  • Jamshed Iqbal, Jean Sévigny, Christa E. Müller. A novel, highly sensitive capillary electrophoresis method for monitoring ecto-nucleotide pyrophosphatases. Second Joint Italian-German Purine Club Meeting Leipzig, Germany, September 12-15, 2007.
  • Christa E. Müller, Jamshed Iqbal, Younas Baqi. Kapillarelektrophorese-Nano-Assays in der Wirkstofftestung. GIT LABOR-FACHZEITSCHRIFT  2006, 10, 897-900.
  • Jamshed Iqbal, 8th International Symposium on Adenosine and Adenine Nucleotides, May 24-28, 2006, University of Ferrara, Italy,
  • Christa E. Müller, Jamshed Iqbal, Younas Baqi. Capillary electrophoresis nano-assays Novel in vitro screening methods in the search for future drugs. Screening - Trends in Drug Discovery 2006, 4, 26-28.
  • Jamshed Iqbal, Herbert Zimmermann, Christa E. Müller. Development of a novel, automated method for the characterization and screening of NTPDase inhibitors by in-capillary enzymatic microreaction. Purinergic Signalling 2006, 2, 170-171.
  • Andreas Brunschweiger, Jamshed Iqbal, Mercedes N. Munkonda, Jean Sévigny, Aileen F. Knowles. Christa E. Müller. Development and structure-activity relationship of ectonucleotidase inhibitors. Purinergic Signalling 2006, 2, 170.
  • Younis Baqi, Jamshed Iqbal, Herbert Zimmermann, Anita Röllich, Holger Stephan, Christa E. Müller. Polyoxometalates – discovery of a new class of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. 3rd Summer School Medicinal Chemistry at the University of Regensburg. “Medicinal Chemistry: Molecular Recognition – Ligand Receptor Interactions”. University of Regensburg, Regensburg, Germany, September 25-27, 2006.
  • Younis Baqi, Jamshed Iqbal, Christa E. Müller. Polyoxometalates - a new class of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Graduiertenkolleg 804 Analyse von Zellfunktionen durch kombinatorische Chemie und Biochemie. Bonn-Aachen International Center For Information Technology B-IT. University of Bonn, Bonn, Germany, October 20, 2006. 
  • Emmerling, F.; Kraus. W. Iqbal, J.; Müller, C.E.; Röllich, A.; Stephan, H.; Polyoxotungstates as potent inhibitors for ecto-nucleotidases. 37th International Conference of Coordination Chemistry. Cape Town, South Africa, 13-18th August 2006.
  • Jamshed Iqbal, Christa E. Müller. Development of a novel, capillary electrophoresis based method for the screening of potential adenosine kinase inhibitors. 14th Camerino-Noordwijkerhout Symposium "Ongoing Progress in the Receptor Chemistry" University of Camerino, Camerino, Italy, September 7-11, 2003.
  • Jamshed Iqbal, “Medicinal Chemistry and Pharmacology of Purinergic Receptors” September 11-13, 2003, University of Camerino, Camerino, Italy.
  • Jamshed Iqbal, 14th Camerino-Noordwijkerhout Symposium "Ongoing Progress in the Receptor Chemistry" September 7-11, 2003, University of Camerino, Camerino, Italy.
  • Jamshed Iqbal, Muhammad Ikram. Determination of lead in roadside soil, gasoline by AAS and UV-Vis spectrophotometer and development of micro emulsion method for the determination of lead in gasoline. Quaid-i-Azam University, Islamabad, Pakistan on October 28-30, 1999.
  • Jamshed Iqbal, 4th DAAD follow-up Seminar (Chemistry) April 29-May 01, 1999, Quaid-i-Azam University Islamabad, Pakistan.