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Label
Abdul Fauq
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Designation:
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Advisor
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Email:
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afauq@cuiatd.edu.pk
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Phone No. :
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N/A
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Role:
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Faculty
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Research Interests:
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Total Synthesis of Natural Products.
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Synthesis and characterization of novel tools of pharmacological interest, especially those related to areas of neurological diseases.
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Developing novel and more efficient isotope-coded tags for Mass Spectrometry.
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Synthesis and characterization of organic compounds that could be used in any area of research in Medicinal Chemistry.
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Publications/Papers
2013
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Journal
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Justine E. Roderick1, J. E.; Gonzalez-Perez1, G. ,Kuksin1, S. A.; Dongre, A.; Roberts, E. R.. , Srinivasan, J.; Andrzejewski Jr. C. A.,Abdul Hafeez Fauq,Golde, T. E.; Miele, L.; Minter, L. M.
"Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. "
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J. Exp. Med.
,Volume 210
,Page 1311-1329.
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2013
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2009
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Journal
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Joshi, I.; Minter, L. M.; Telfer, J.,Demarest, R. M.; Capobianco, A. J.; Aster, J, C., Sicinski, P.,Abdul Hafeez Fauq,Golde, T. E.; Osborne, B. A.
"Notch signaling mediates G1/S cell cycle progression in T cells via cyclin D3 and its dependent kinases"
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Blood
,Volume 113
,Page 1189-98.
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2009
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2008
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Journal
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Kukar, T. L.; Ladd, T. B.; Bann, M. A.,Fraering, P. C.; Narlawar, R.; Maharvi, G. M.,Healy, B. Chapman, R.; Welzel, A. T.,Price, R. W.; Moore, B; Rangachari, V.,Cusack, B.; Eriksen, E; Jansen-West, K.,Verbeeck, C.; Debra D.; Eckman, C., Ye, W.; Sagi, S.; Cottrell, B. A.,Torpey, J. Rosenberry, T. L,Abdul Hafeez Fauq,Wolfe, M. S. M. W.; Schmidt, B.; Walsh, D. A., Koo, E. H.; Golde, T. E
"Substrate-targeting gamma-secretase modulators"
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Nature
,Volume 453
,Issue 7197
,Page 925-929
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2008
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2006
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Journal
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Pockaj, B. A.; Gallagher, J. G.; Loprinzi, C.. ,Stella, P. J.; Barton, D. L.; Sloan, J. A.. ,Lavasseur, B. I.; Rao, R. M.; Fitch, T, M.,Rowland, K. M.; Novotny, P. J.; Flynn, P. J. , Richelson, E.,Abdul Hafeez Fauq
"A Phase III Double-Blind, Randomized, Placebo-Controlled Crossover Trial of Black Cohosh in the Management of Hot Flashes: NCCTG Trial N01CC1"
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J. Clin. Oncol.
,Volume 24
,Issue 18
,Page 2836-2841
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2006
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Shin, H. M.; Minter.; L. M.; Chom, O. H.,Gottipati;, S.,Abdul Hafeez Fauq,Golde, T. E.; Sonenshein, G. E.; Osborne, B. A.
"Notch1 augments NF-kappa B activity by facilitating its nuclear retention"
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Embo Journal .
,Volume 25
,Page 129-138
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2006
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2005
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Journal
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Kukar T1, Murphy MP, Eriksen JL, Sagi SA,Weggen S, Smith TE, Ladd T,Khan MA, Kache R, Beard J, Dodson M, Merit S, Ozols VV, Anastasiadis PZ, Das P,Abdul Hafeez Fauq,Koo EH, Golde TE.,Merit S, Ozols VV, Anastasiadis PZ, Das P
"Diverse compounds mimic Alzheimer disease-causing mutations by augmenting A beta 42 production"
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Nature Medicine
,Volume 11
,Page 545-550
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2005
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Minter, L.M.. ,Turley, D. M.; Das, P.; Shin, H. M.; Joshi, I , Lawlor, R. G.; Cho, O. H.; Palaga, T,Gottipati, S.; Telfer, J. C.; Kostura, L.,Abdul Hafeez Fauq,Simpson, K.; Such, K. A.; Miele, L.,Golde, T. E.; Miller, S. D.; Osborne, B. A.
"Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. "
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Nature Immunology
,Volume 6
,Page 680 - 688
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2005
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1999
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Journal
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Tyler, B.; Jansen, K.; Mccormick, D. J.,Douglas, C. L.;, Boules, M.; Stewart, J. A,Zhao, L.; Lacy, B.; Cusack, B.,Abdul Hafeez Fauq,Richelson, E
"Peptide Nucleic Acids Targeted to the Neurotensin Receptor and Administered I.P. Cross the Blood-brain Barrier and Specifically Reduce Gene Expression."
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Proc. Natl. Acad. Sci. USA.
,Volume 96
,Page 7053-7058.
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1999
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1993
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Journal
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A. P. Kozikowski,V. I. Ognyanov,Abdul Hafeez Fauq,Wilcox, R. A.; Nahorski, S. R.
"Synthesis of 1D-3-Deoxy-, 1D-2,3-Dideoxy-, and 1D-2,3,6-Trideoxy-myo-Inositol 1,4,5-Trisphosphate from Quebrachitol, Their Binding Affinities and Calcium Release Activity"
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J. Am. Chem. Soc. .
,Volume 115
,Issue 11
,Page 4429-4434
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1993
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1990
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Journal
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Alan P. Kozikowski,Abdul Hafeez Fauq,Ibrahim A. Aksoy, Markus J. Seewald, Garth Powis
". Synthesis of the First Optically Pure, Fluorinated Inositol 1,4,5-Tris-phosphate of myo-Inositol Stereochemistry and Its Effect on Ca2+Release in Swiss 3T3 cells"
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J. Am. Chem. Soc. .
,Volume 112
,Issue 20
,Page 7403-7404
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1990
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