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Pharmaceutical Chemistry Research Group
2025
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Dr. Nighat Fatima,A.Mumtaz,I.Shahzadi,A. Mannan
"Bioactive Secondary Metabolites from Bauhinia variegata Linn. Roots: Isolation, Characterization, and Cytotoxic Evaluation. Current Pharmaceutical Design. 31(15),1239 - 1246" ,
Bioactive Secondary Metabolites from Bauhinia variegata Linn. Roots: Isolation, Characterization, and Cytotoxic Evaluation. Current Pharmaceutical Design. 31(15),1239 - 1246
,Volume 31
,Issue 15
,Page 1239-1246
, 2025
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2023
Publications
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Journal
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A. Mannan,T.Ismail,Dr. Nighat Fatima,Sohail Anjum Shahzad,Shujaat A.K, SA Khan
"Synthesis, In Vitro Investigation and Molecular Docking Studies of Novel Quinoline Analogues: A Drug repositioning approach from Amodiaquine." ,
Journal of Xi’an Shiyou University, Natural Science Edition
,Volume 19
,Issue 6
,Page 1057-1076
, 2023
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2022
Publications
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Journal
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Dr. Nighat Fatima,I.Shahzadi,A. Mannan,T.Ismail,N. Riaz,K.Yousaf,Ihsan-ul-Haq,Saniya Zahra,MH Asim
"Phytochemical and biological attributes of Bauhinia variegata L. (Caesalpiniaceae). " ,
Brazilian Journal of Biology
,Volume 82
,Page 1-10
, 2022
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Dr. Nighat Fatima,I.Shahzadi,A. Mannan,Dr. M. Arfat Yameen,T.Ismail,I.Amirzada,Syed Aun Muhammad,Hina Tariq,G. Murtaza
"Photodynamic cytotoxic and antibacterial evaluation of Tecoma stans and Narcissus tazetta mediated silver nanoparticles" ,
Arabian Journal of Chemistry
,Volume 15
,Issue 13
,Page 103652-62
, 2022
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Nikhat Ilahi,Safia Ahmed,Dr. Nighat Fatima,Abdul Haleem,Sajjad Iqbal,Waseem Sajjad ,Abubakar Sideeqe
"Biosynthesis of silver nanoparticles using endophytic Fusarium oxysporum strain NFW16 and their in vitro antibacterial potential" ,
Microscopy research and technique
,Volume 85
,Issue 4
,Page 1568-1579
, 2022
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Jean P. Dzoyem,G. Murtaza,I.Shahzadi,A. Mannan,Dr. M. Arfat Yameen,T.Ismail,Dr. Nighat Fatima,Dr. Jamshed Iqbal,,Roland T. Tchuenguem
"Anticandidal activity of green synthesized silver nanoparticles and extract loaded, chitosan nanoparticles of Euphorbia prostata" ,
Artificial Cells, Nanomedicine, and Biotechnology
,Volume 50
,Issue 1
,Page 188-197
, 2022
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Asad. M.H.H.B,A. Mannan
"Multifunctional toxin phospholipase A2 (PLA2) in Naja oxiana venom, a promising target for 2,5-disubstituted-1,3,4-oxadiazole derivatives" ,
CURRENT SCIENCE
,Volume 123
,Issue 5
,Page 650-657
, 2022
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2021
Publications
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Journal
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Dr. Jamshed Iqbal,Hafiz Saqib Ali,Behzad Jafari,Sumera Zaib,Abdul Hameed,Peter Langer,Yasser MSA Alkahraman,Shafiq Ur Rahman
"Structure-Based Virtual Screening of Dipeptidyl Peptidase 4 Inhibitors and their In vitro Analysis."" ,
Computational Biology and Chemistry
,Volume 91
,Page 107326
, 2021
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Dr. Jamshed Iqbal,Humaira Nadeem,sumaira zeb,sadia sarwer,Hafiz Saqib Ali,Muazzam Arif,A. Imran,S. ur Rahman,Mohsinul Mulk Bacha
"Rhodanine-3-acetamide derivatives as aldose and aldehyde reductase inhibitors to treat diabetic complications: synthesis, biological evaluation, molecular docking and simulation studies" ,
BMC Chemistry
,Volume 15
,Page 28 2021
, 2021
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Dr. Jamshed Iqbal, Randa El-Gamal,Julie Pelletier,Jean Sévigny,Hanan S. Anbar,S. Ullah,Mohammed I. El-Gamal
"Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents" ,
European Journal of Medicinal Chemistry
,Volume 217
,Page 113339
, 2021
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Dr. Jamshed Iqbal,Abdul Hameed,Mariya al-Rashida,Marium Bibi,Maliha Uroos,Asnuzilawati Asari,Shafia Iftikhar,Habsah Mohamad,Muhammad Nawaz Tahir,Zahid Shafiq,Jamshed Iqbal,A. Imran,Muhammad Tariq Shehzad
"Exploring Synthetic and Therapeutic Prospects of New Thiazoline Derivatives as Aldose Reductase (ALR2) Inhibitors" ,
RSC Advances
,Volume 11
,Page 17259-17282
, 2021
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Dr. Jamshed Iqbal,Musarrat Adnan,Muhammad Waqar Hameed,Abdul Wajid Khalil,Zafar Iqbal,Daniel C Hoessli,Muhammad Shahid,Shafi Ullah Khan,Saifullah Afridi
"Small organic molecules accelerate the expansion of regulatory T cells" ,
Bioorganic Chemistry
,Volume 111
,Page 104908
, 2021
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Dr. Jamshed Iqbal,Rubina Munir,Faryal Chaudhry,sumera zaib,Ayesha Muzaffar,A. Imran,Noman Javid
"Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition" ,
Bioorganic Chemistry
,Volume 99
,Page 103852
, 2021
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Dr. Jamshed Iqbal,Ajmal Khan,Sobia Ahsan Halim,Abdul Hameed,Zahid Shafiq ,A. Imran,Muhammad Tariq Shehzad
"Synthesis of indole substituted thiosemicarbazones as an aldose reductase inhibitor: an in vitro, selectivity and in silico study" ,
Future Medicinal Chemistry
,Volume 13
,Issue 14
,Page 1185-1201
, 2021
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Conference
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Dr. Jamshed Iqbal, Aamer Saeed,Dilawar Hussain,Markus Kalesse,Syeda Aaliya Shehzadi,Jamshed Iqbal,S. Afzal,Pervaiz Ali Channar
"Hydrazine clubbed 1,3-thiazoles as potent urease inhibitors: design, synthesis and molecular docking studies" ,
Molecular Diversity
, 2021
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2020
Publications
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Journal
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Dr. Nighat Fatima,Dr. M. Arfat Yameen,I.Shahzadi,Dr. Jamshed Iqbal,Muhammad Raf
"Datura suaveolens and Verbena tenuisecta mediated silver nanoparticles, their photodynamic cytotoxic and antimicrobial evaluation" ,
11, February
,Volume 36
,Issue 2
,Page 31
, 2020
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Muhammad Latif,Muhammad Ihtisham Umar,Asim Rahim,Shujaat A.K, SA Khan,Dr. Nighat Fatima, Izhar Hussain,A. Mannan,Mohamed Khadeer Ahamed Basheer
"Isolation and biological evaluation of some secondary metabolites from seeds of Silybum marianum" ,
1 March
,Volume 16
,Issue 68
,Page 93
, 2020
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Dr. Jamshed Iqbal,Emine Ulker,Sumera Zaib,Khurshid Ayub,F. Rashid,Saghir Abbas
"Anticancer evaluation of a Manganese Complex on HeLa and MCF-7 Cancer Cells: Design, Deterministic Solvothermal Synthesis Approach, Hirshfeld analysis, DNA Binding, Intracellular Reactive Oxygen Species (ROS) Production, Electrochemical Characterization and Density Functional Theory" ,
Journal of Biomolecular Structure & Dynamics
,Volume 20
,Issue 03
,Page 1726818
, 2020
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Ehsan Ullah Mughal,Hafiz Umar Farooq, Amina Sadiq, Hummera Rafique,Sajjad Hussain Sumrra,Muhammad Naveed Zafar,Dr. Nighat Fatima,Syed Aun Muhammad,A. Mannan, Chaudhary Omer Javed,, Muhammad Tayyab
"An Efficient Protocol for the Synthesis, Biological Screening and Molecular Docking Studies of 3,4-Dihydropyrimidine-2-one/thione Derivatives" ,
20 April
,Volume 17
,Issue 3
,Page 330-340
, 2020
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Dr. Jamshed Iqbal,Ghulam Murtaza,Albert A. Rizvanov,S. Ali,Asad. M.H.H.B,, Fahad Khan
"Biological Evaluation of Newly Synthesized Biaryl Guanidine Derivatives to Arrest β-Secretase Enzymatic Activity Involved in Alzheimer’s Disease" ,
BioMed Research International
,Volume 2020
,Page 8934289
, 2020
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Dr. Jamshed Iqbal,Abdul Hameed,Jean Sévigny,Farwa Batool,Asnuzilawati Asari,Habsah Mohamad,Julie Pelletier,Mariya al-Rashida,A. Mahmood,S.Jadoon,Hafiza Amna Younus
"Design, Synthesis and Investigation of Ectonucleotidase (ALP & e5′NT) Inhibition Activities" ,
Bioorganic Chemistry
,Volume 100
,Issue 2020
,Page 103827
, 2020
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Dr. Jamshed Iqbal,Asma Khurshid,Ghulam Shabir,A. Mahmood,S.Zaib,Aamer Saeed
"An Efficient Synthetic Approach Toward a Sporadic Heterocyclic Scaffold: 1,3-Oxathiol-2-ylidenes; Alkaline Phosphatase Inhibition and Molecular Docking studie" ,
Bioorganic & Medicinal Chemistry Letters
,Volume 30
,Issue 13
,Page 127238
, 2020
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A. Mannan,Asad. M.H.H.B,Dr. M. Arfat Yameen,I.Amirzada,Shujaat A.K, SA Khan
"Effect of varying quantities of polymer on preparation and stability evaluation of carbamazepine cocrystals with dicarboxylic acid coformers" ,
Pakistan Journal of Pharmaceutical Sciences
,Volume 33
,Issue 4
,Page 1755-1761
, 2020
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Dr. Jamshed Iqbal,S. Afzal,S.Zaib,Peter Langer
"Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7-trifluoromethyl-thiadiazolopyrimidones Scaffold" ,
Medicinal Chemistry
,Volume 20
,Issue 5
,Page 689-702
, 2020
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Dr. Jamshed Iqbal,Sumera Zaib,Aamer Saeed,Jean Sévigny,Julie Pelletier,A.Mumtaz,A. Mahmood,Kiran Saeed
"Bis thioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and Intestinal alkaline phosphatase (IAP) inhibitors: Synthesis and molecular docking studies." ,
Bioorganic Chemistry
,Volume 110
,Page 103996
, 2020
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Dr. Jamshed Iqbal,, Muzammal Hussain,Syeda Abida Ejaz,Jean Sevigny,Muhammad Farman,Masoom Yasinzai,Jiancun Zhang,Hina Andleeb
"Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): a therapeutic target against vascular calcification" ,
Bioorganic Chemistry
,Volume 101
,Page 103999
, 2020
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Dr. Jamshed Iqbal,Sumera Zaib, Aamer Saeed, Julie Pelletier,Jean Savigny,A. Mahmood,Hamid Aziz Wazir
"New hybrid scaffolds based on carbazole-chalcones as potent anticancer agents." ,
Journal of Biomolecular Structure & Dynamics
,Volume 108
,Page 108456
, 2020
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Dr. Jamshed Iqbal,Sumera Zaib,Aamer Saeed,Zahid Shafiq,A. Mahmood,Hamid Aziz
"Synthesis, characterization, in vitro tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibition studies and computational evaluation of novel thiazole derivatives" ,
Bioorganic Chemistry
,Volume 102
,Page 104088
, 2020
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Dr. Jamshed Iqbal,Muhammad Ashfaq Khan,Ruqaiya Khalil,Zaheer Ul-Haq,Amir Mushtaq,Rabia Qaiser, Faisal Usman
"Preparation and characterization of anticancer niosomal withaferin–A formulation for improved delivery to cancer cells: In vitro, in vivo, and in silico evaluation" ,
Journal of Drug Delivery Science and Technology
,Volume 59
,Page 101863
, 2020
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Dr. Jamshed Iqbal,Abida Ashraf,Muhammad Nawaz Tahir,Muhammad Yaqub,Jamshed Iqbal,S.Jadoon,Zahid Shafiq
"Synthesis, Characterization and In Silico Studies of Novel Spirooxindole Derivatives as Ecto-5′-Nucleotidase Inhibitors " ,
ACS Medicinal Chemistry Letters
,Volume 11
,Issue 12
,Page 2397–2405
, 2020
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Zainab Jamil,Syeda Tahira Qousain Naqvi,Sumaira Rasul,Syed Bilal Hussain,Dr. Nighat Fatima,Muhammad Imran Qadir,Syed Aun Muhammad
"Antibacterial activity and characterization of zinc oxide nanoparticles synthesized by microalgae" ,
1 November
,Volume 33
,Issue 6
,Page 2497-2504
, 2020
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Ehsan Ullah Mughal,Masoud Mirzaei,Amina Sadiq,Sana Fatima,Ayesha Naseem,Nafeesa Naeem,Dr. Nighat Fatima,Samia Kausar,Ataf Ali Altaf,Muhammad Naveed Zafar,Bilal Ahmad Khan
"Terpyridine-metal complexes: effects of different substituents on their physico-chemical properties and density functional theory studies" ,
25 November
,Volume 7
,Issue 11
,Page 1
, 2020
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2019
Publications
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Journal
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Dr. Jamshed Iqbal,S. ur Rahman,S.Zaib
"Carbonic anhydrase inhibitory potential of Flurbiprofen, Ibuprofen and 4-Tert-butylbenzoic hydrazide Derivatives: Design, synthesis, characterization, biochemical evaluation, molecular docking and dynamic studies. " ,
Medicinal Chemistry
,Volume 15
,Issue 3
,Page 298-310
, 2019
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Dr. Jamshed Iqbal,S. Jalil,S.Zaib
"Synthesis, X-ray crystal and monoamine oxidase inhibitory activity of 4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine 5,5-dioxides: In vitro studies and docking analysis. " ,
European Journal of Pharmaceutical Sciences
,Volume 131
,Page 9-22
, 2019
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A. Mannan,M. Sohail,Shujaat A.K, SA Khan
"Facile Synthesis of Chitosan Based-(AMPS-co-AA) Semi-IPNs as a Potential Drug Carrier: Enzymatic Degradation, Cytotoxicity, and Preliminary Safety Evaluation" ,
Current Drug Delivery, 2019
,Volume 16
,Page 242-253
, 2019
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Dr. Jamshed Iqbal,S. Ullah,S. Jalil,S.Zaib
"Synthesis, biological evaluation, and molecular docking study of sulfonate derivatives as nucleotide pyrophosphatase/ phosphodiesterases (NPP) inhibitors. " ,
Bioorganic & Medicinal Chemistry
,Volume 27
,Issue 13
,Page 2741-2752
, 2019
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Anam Shahzadi,Fakhera Ikram,Riaz Ul Haq Subhani,Arsalan Ahmed,Anila Asif,Dr. Nighat Fatima,Aqif Anwar Chaudhry,Yong Hu
"Acid susceptible polymeric stealthy nanoparticles for improved anticancer drug delivery" ,
11 December
,Volume 68
,Issue 18
,Page 1187-1196
, 2019
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Dr. Jamshed Iqbal,Abdul Hameed, Mariya al-Rashida,Maliha Uroos,Asnuzilawati Asari,Habsah Mohamad,Muhammad Islam,Shafia Iftikhar, Zahid Shafiq,A. Imran,Muhammad Tariq Shehzad
"Exploring antidiabetic potential of adamantyl-thiosemicarbazones via aldose reductase (ALR2) inhibition" ,
Bioorganic Chemistry
,Volume 92
,Page 103244
, 2019
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Book/Chapter
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2018
Publications
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Journal
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Dr. Jamshed Iqbal,Abdul Hameed,Jonna Lecka,Jean Sevigny,A.Ejaz,Jawad Shah,Aamer Saeed
"Distinctive inhibition of alkaline phosphatase isozymes by thiazol‐2‐ylidene‐benzamide derivatives: Functional insights into their anticancer role" ,
Journal of Cellular Biochemistry
,Volume 119
,Issue 8
,Page 6501-6513
, 2018
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A. Mannan,A.Nazir,Dr. Nighat Fatima,Shujaat A.K, SA Khan,Yasser MSA Alkahraman
"Antioxidants, antimicrobial and cytotoxic potential of Swertia chirata" ,
Biomedical Research, September 01, 2018
,Volume 29
,Issue 13
,Page 2722-2726
, 2018
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2017
Publications
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Journal
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Dr. Jamshed Iqbal,Peter Ehlers,Alexander Villinger,Eva Frank,Gyula Schneider,Janos Wolfling,Qamar Rahman,Peter Langer,A.Ejaz,Jawad Shah,Anton Ivanov
"Synthesis, functionalization and biological activity of arylated derivatives of (+)-estrone" ,
Bioorganic & Medicinal Chemistry
,Volume 25
,Issue 3
,Page 949-962
, 2017
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Asad. M.H.H.B,Izhar Hussain,Anna katherina Jager
"ICP-OES analysis of Naja naja karachiensis venom: Inorganic ions for turning on and off enzymatic actions. " ,
Current Science, 2, February, 2017
,Volume 112
,Issue 3
,Page 45-460
, 2017
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Naqvi, Syeda Tahira Qousain,Shah, Ziaullah;,Dr. Nighat Fatima,Qadir, Muhammad Imran,Ali, Amjad,Muhammad, Syed Aun
"Characterization and Biological Studies of Copper Nanoparticles Synthesized by Aspergillus niger" ,
1 April
,Volume 11
,Issue 2
,Page 136-140
, 2017
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Dr. Nighat Fatima, Ui J. Youn, Safia Ahmed, Ihsan ul-Haq,Ulyana Munoz-Acuna,Charles J. Simmons, Muneer A. Qazi, Muniba Jadoon, Ghee T. Tan, Tawanun Sripisut, Esperanza J.C. de Blanco, Leng C. Chang
"Bioactive Constituents from an Endophytic Fungus, Penicillium polonicum NFW9, Associated with Taxus fauna." ,
Journal
,Volume 13
,Issue 7
,Page 689-697
, 2017
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Dr. Nighat Fatima,Abida K Khan,A.Maalik,A. Mannan,A.Mumtaz
"Fungal Metabolites and Antimalarial Drug Discovery; A Review" ,
Acta Poloniae Pharmaceutica-Drug Research, October 23, 2017
,Volume 74
,Issue 5
,Page 1327-1341
, 2017
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A. Mannan
"Adsorption of Ni2+, Hg2+, Pb2+, Cr3+, and Co2+ on iron oxide nanoparticles immobilized on cellulose fiber: equilibrium, kinetic, thermodynamic, mechanisms, and statistical supposition" ,
Desalination and Water Treatment, November 01, 2017
,Volume 95
,Page 234-246
, 2017
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2016
Publications
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Journal
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Dr. Nighat Fatima,Syed Aun Muhammad,Ibrar Khan,I.Shahzadi,A.Mumtaz,Muneer Ahmed Qazi,Muhammad Ali Hashmi,Abida K Khan,T.Ismail
"Chaetomium endophytes: a repository of pharmacologically active metabolites" ,
Acta Physiologiae Plantarum
,Volume 83
,Issue 6
,Page 136
, 2016
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Dr. Jamshed Iqbal,Sebastian Boldt,Zaib un Nisa,Peter Ehlers,Alexander Villinger,Gyula Schneider,Janos Wolfling,Qamar Rahman,Peter Langer,Jawad Shah,Anton Ivanov
"Synthesis and phosphatase inhibitory activity of 3-alkynylestrones and their derivatives" ,
RSC Advances
,Volume 6
,Issue 14
,Page 11118-11127
, 2016
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Hina Tariq,Muhammad Soaib Said,Muhammad Dawood,Dr. Nighat Fatima,A.Mumtaz,I.Shahzadi,Syed Aun Muhammad
"Fungal Metabolites and Leishmaniasis: A Review" ,
20 June
,Volume 12
,Issue 2
,Page 1-12
, 2016
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Ibrar Khan,Sadia Qayyum,Shehzad Ahmed,Zeeshan Niaz,Zhen-Ming Chi,Dr. Nighat Fatima
"Molecular cloning and sequence analysis of a PVGOX gene encoding glucose oxidase in Penicillium viticola F1 strain and it's expression quantitation." ,
July 15
,Volume 1119
,Issue 16
,Page 30558-3
, 2016
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Zainab Gul Kanwal,Abdul Hafeez,Ihsan Ul Haq,Tofeeq-Ur-Rehman,Syed Aun Muhammad,I.Shahzadi,Dr. Nighat Fatima,.Nisar-ur-Rahman
"Antioxidant, Antimicrobial and Antileishmanial Study of Different Parts of Peganum harmala" ,
July 18
,Volume 9
,Issue 1
,Page 45-58
, 2016
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Dr. Jamshed Iqbal,Imtiaz Khan,Shahid Hameed,Jawad Shah,Y.tehseen,Hina Andleeb
"Identification of novel pyrazole–rhodanine hybrid scaffolds as potent inhibitors of aldose reductase: design, synthesis, biological evaluation and molecular docking analysis" ,
RSC Advances
,Volume 6
,Issue 81
,Page 77688-77700
, 2016
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Dr. Jamshed Iqbal,Zaib un Nisa,Joanna Lecka,Jean Sevigny,Jurgen Bajorath,Aamer Saeed,Jawad Shah,S. Hassan,Parvaiz Ali Channar
"Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto‐5′‐nucleotidase" ,
Chemical biology & drug design
,Volume 89
,Issue 3
,Page 365-370
, 2016
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A. Mannan,Syed Aun Muhammad,Fareeha Anwar,I.Amirzada,.Nisar-ur-Rahman,Dr. Nighat Fatima,T.Ismail
"AN EMERGING PARADIGM EXOSOMES: COMPOSITION, BIOLOGICAL FUNCTIONS, AND DIAGNOSTIC AND THERAPEUTIC POTENTIALS" ,
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, October 2016
,Volume 3
,Issue 10
,Page 1297-1308
, 2016
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T.Ismail,Syed Aun Muhammad,Fareeha Anwar,.Nisar-ur-Rahman,A. Mannan,Dr. Nighat Fatima
"BIOLOGICAL SCREENING OF ENDOPHYTIC FUNGI ISOLATED FROM NERIUM OLEANDER " ,
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, November 2016
,Volume 3
,Issue 11
,Page 1322-1329
, 2016
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Dr. Jamshed Iqbal,Viktor O. laroshenko,Alexander Villinger,Vyacheslav Ya. Sosnovskikh,Afshin Abbasi,Peter Langer,A.Ejaz,Jawad Shah,Iryna Savych
"Reactions of 3‐Acylchromones with Heterocyclic Ketene Aminals: One‐Pot Synthesis and Phosphatase Inhibitory Activity of Fused Pyridine Derivatives" ,
European Journal of Organic Chemistry
,Volume 2017
,Issue 1
,Page 186-202
, 2016
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2015
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Journal
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Dr. Jamshed Iqbal,Syeda T.Zehra,Khalid M. Khan,Rima D. Alharthy,Norbert Furtmann,Jurgen Bajorath,Muhammad N. Tahir,Jawad Shah,Abdul Hameed
"Syntheses, Cholinesterases Inhibition, and Molecular Docking Studies of Pyrido[2,3-b]pyrazine Derivatives" ,
Chemical Biology & Drug Design
,Volume 86
,Issue 5
,Page 1115-1120
, 2015
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Dr. Jamshed Iqbal,Aliya Ibrar,Shahid Hameed,Joanna Lecka,Jose Luis Millan,Jean Sevigny,Jawad Shah,A.Ejaz,Imtiaz Khan
"Investigation of quinoline-4-carboxylic acid as a highly potent scaffold for the development of alkaline phosphatase inhibitors: synthesis, SAR analysis and molecular modelling studies" ,
RSC Advances
,Volume 5
,Issue 1
,Page 64404-64413
, 2015
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Dr. Jamshed Iqbal,Aliya Ibrar,Shafi Ullah Khan,Shahid Hameed,Jim Simpson,Joanna Lecka,Jean Sevigny,A.Ejaz,Jawad Shah,Imtiaz Khan
"Influence of the diversified structural variations at the imine functionality of 4-bromophenylacetic acid derived hydrazones on alkaline phosphatase inhibition: synthesis and molecular modelling studies" ,
RSC Advances
,Volume 5
,Issue 1
,Page 90806-90818
, 2015
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Dr. Jamshed Iqbal,Andranik Petrosyan,Raji Akeem Adewale,Peter Ehlers,Tatevik Grigoryan,Anna F. Mkrtchyan,Zorayr Z. Mardiyan,Ani J. Karapetyan,Avetis H. Tsaturyan,Ashot S. Saghyan,Peter Langer,Jawad Shah,Silvio Parpart
"Synthesis of optically pure (S)-2-amino-5-arylpent-4-ynoic acids by Sonogashira reactions and their potential use as highly selective potent inhibitors of aldose reductase" ,
RSC Advances
,Volume 5
,Issue 130
,Page 107400-107412
, 2015
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2014
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Journal
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Dr. Jamshed Iqbal
"Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazines" ,
15 March 2014
, 2014
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Conference
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2012
Publications
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Journal
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S.Zaib,Dr. Jamshed Iqbal
"Synthesis, Urease Inhibition, Antioxidant and Antibacterial Studies of Some 4-Amino-5-aryl-3H-1,2,4-triazole-3-thiones and their 3,6-Disubstituted 1,2,4-Triazolo[3,4-b]1,3,4-thiadiazole Derivatives" ,
Journal of the Brazilian Chemical Society
,Volume 5
,Issue 23
,Page 854–860
, 2012
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S.Zaib,K.Shoaib,Dr. Jamshed Iqbal
"Synthesis, urease inhibition, antioxidant, antibacterial, and molecular docking studies of 1,3,4-oxadiazole derivatives." ,
International Scholarly Research Network
ISRN Pharmacology
, 2012
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Asad. M.H.H.B
"The adsorption studies of non-ionic surfactants (tween 20, tween 40 and tween 80) were conducted at olive oil-water, sunflower oil-water and corn oil-water interfaces by ring detachment method with a du Nouy Tensiometer at 20 °C. A decrease in interfacial tension with an increase in surfactant concentration was observed at all the oil-water interfaces under investigation. Surface excess was calculated from Gibb’s equation while area per molecule was computed from surface excess. Surface pressure-area curves were plotted to study the states of films formed. On close examination of π-A graphs, it was indicated that all the graphs have three distinct parts. The extreme left portion (a) of the graphs represents condensed state, called solid film region, the curved region (b) of the π-A graphs corresponds to liquid film region, while the gaseous film region (c) is indicated by the shallow right hand part of the curves. The solid film region was more prominent in corn oil-water system while a more distinct gaseous film region was observed in olive oil-water system than in other oil-water systems studied. However, liquid film region was observed in all the systems investigated. The observed difference in the behaviour of surfactants at different vegetable oil-water interfaces could be attributed to the difference in types of interacting forces between the surfactant molecules and various vegetable oil phases." ,
Latin American Journal of Pharmacy
,Volume 31
,Issue 6
,Page 864-868
, 2012
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Dr. Jamshed Iqbal
"Synthesis, Acetylcholinesterase and Alkaline Phosphatase Inhibition of Some New 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives" ,
Australian Journal of Chemistry
,Volume 65
,Issue 10
,Page 1413-1419
, 2012
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